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Silenor (doxepin) is available in 3 mg and 6 mg strength tablets for oral administration. Each tablet contains 3.39 mg or 6.78 mg doxepin hydrochloride, equivalent to 3 mg and 6mg of doxepin, respectively. Doxepin is a medication primarily used for the treatment of insomnia. It contains the active ingredient doxepin, which is classified as a tricyclic antidepressant. In this response, I will provide you with information on Doxepin including its uses, mechanism of action, dosage, side effects, and precautions.
Uses:
Silenor is primarily prescribed for the treatment of insomnia, particularly difficulty in falling asleep. It is approved for use in adults aged 18 years and older. Insomnia is a common sleep disorder characterized by difficulty in falling asleep or staying asleep, resulting in daytime impairment and distress.
Mechanism of Action:
Doxepin, the active ingredient in Silenor, acts as a histamine H1 receptor antagonist. By blocking the histamine receptors in the brain, Silenor reduces wakefulness and promotes sleep. It also has sedative effects, which contribute to its sleep-promoting properties.
Dosage:
The recommended starting dose of Silenor for adults is 6 mg taken once daily, within 30 minutes before bedtime. The dosage can be increased to 6 mg or 12 mg based on individual response and tolerability. Silenor should be swallowed whole and not crushed, chewed, or divided.
Side Effects:
Like any medication, Silenor may cause side effects. Common side effects include drowsiness, dizziness, dry mouth, fatigue, headache, and upset stomach. These side effects are generally mild and temporary. However, if they persist or worsen, it is important to consult a healthcare professional.
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Less common but potentially serious side effects may include allergic reactions, rapid or irregular heartbeat, difficulty urinating, and changes in mood or behavior. If any of these occur, it is important to seek medical attention immediately.
Precautions:
Before taking Doxepin it is important to inform your healthcare provider about any medical conditions you have, especially if you have a history of heart problems, liver disease, urinary retention, or glaucoma. Silenor may also interact with other medications, so it is important to disclose all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements.
Doxepin may cause drowsiness and impair your ability to drive or operate machinery. It is advised to avoid consuming alcohol while taking Silenor, as it can increase the sedative effects of the medication. It is important to follow your healthcare provider’s instructions and dosage recommendations when taking Silenor. If you have any concerns or questions about the medication, it is best to consult your healthcare provider for personalized advice.
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Please note that this information is not exhaustive, and it is always recommended to consult a healthcare professional or refer to the medication’s package insert for comprehensive and up-to-date information on Silenor. Chemically, doxepin hydrochloride is an (E) and (Z) geometric, isomeric mixture of 1 propanamine, 3-dibenz[b,e]oxepin-11(6H)ylidene-N,N-dimethyl-hydrochloride.
SILENOR (doxepin tablets) is a hypnotic (sleep) medicine that is used to treat people who have trouble staying asleep. Doxepin hydrochloride is a white crystalline powder, with a slight amine-like odor, that is readily soluble in water. It has a molecular weight of 315.84 and molecular formula of C19H21NO•HCl. Buy Doxepin Online
Each Silenor (doxepin tablets) tablet includes the following inactive ingredients: microcrystalline cellulose, colloidal silicon dioxide, and magnesium stearate. The 3 mg tablet also contains FD&C Blue No.1. The 6 mg tablet also contains D&C Yellow No. 10 and FD&C Blue No. 1.
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Silenor Dosage and Administration
Silenor (doxepin tablets) is indicated for the treatment of insomnia characterized by difficulty with sleep maintenance. The clinical trials performed in support of efficacy were up to 3 months in duration. The dose of Silenor (doxepin tablets) should be individualized. Buy Silenor Online
Dosing in Adults
The recommended dose of doxepin tablets for adults is 6 mg once daily. A 3 mg once daily dose may be appropriate for some patients, if clinically indicated.
Dosing in the Elderly
The recommended starting dose of doxepin tablets in elderly patients ( ≥ 65 years old) is 3 mg once daily. The daily dose can be increased to 6 mg, if clinically indicated.
Administration
doxepin tablets) should be taken within 30 minutes of bedtime. To minimize the potential for next day effects, doxepin tablets should not be taken within 3 hours of a meal.
Side Effects of Silenor Medication
The pre-marketing development program for Silenor included doxepin HCl exposures in 1017 subjects (580 insomnia patients and 437 healthy subjects) from 12 studies conducted in the United States. 863 of these subjects (580 insomnia patients and 283 healthy subjects) participated in six randomized, placebo-controlled efficacy studies with Silenor (doxepin tablets) doses of 1 mg, 3 mg, and 6 mg for up to 3-months in duration.
Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice. However, data from the doxepin tablets studies provide the physician with a basis for estimating the relative contributions of drug and non-drug factors to adverse reaction incidence rates in the populations studied.
Precautions for Buy Silenor Online
Because sleep disturbances may be the presenting manifestation of a physical and/or psychiatric disorder, symptomatic treatment of insomnia should be initiated only after careful evaluation of the patient.
The failure of insomnia to remit after 7 to 10 days of treatment may indicate the presence of a primary psychiatric and/or medical illness that should be evaluated. Exacerbation of insomnia or the emergence of new cognitive or behavioral abnormalities may be the consequence of an unrecognized psychiatric or physical disorder. Such findings have emerged during the course of treatment with hypnotic drugs.
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How is Silenor used
Before starting Doxepin it is important to consult with a healthcare professional who can evaluate your condition and determine if this medication is appropriate for you. They will consider factors such as your medical history, current medications, and any other underlying health conditions you may have.
Doxepin tablets come in different strengths, typically ranging from 3 mg to 6 mg. The dosage prescribed will depend on various factors, including the severity of your insomnia and your response to the medication. Your healthcare provider will determine the appropriate dosage for you and provide specific instructions on how to take Doxepin
It is important to take Silenor exactly as prescribed. The medication should be taken about 30 minutes before bedtime. The tablet should be swallowed whole with a glass of water, without crushing or chewing it. Doxepin can be taken with or without food, but it is generally recommended to take it on an empty stomach to maximize its effectiveness.
It is important to maintain a consistent sleep schedule while taking Doxepin Try to go to bed at the same time each night and wake up at the same time each morning, even on weekends or days off. This helps regulate your body’s internal clock and improve the quality of your sleep.
Avoid consuming alcohol while taking Doxepin as it can increase the sedative effects of the medication and impair your coordination and alertness. Additionally, it is important to avoid other sedating substances or medications that can interact with Doxepin and cause excessive drowsiness. Doxepin generally intended for short-term use, typically for up to 4 weeks. If your insomnia persists or worsens after this period, it is important to consult with your healthcare provider to reevaluate your treatment plan.
As with any medication, Doxepin may cause side effects. Common side effects include drowsiness, dizziness, dry mouth, blurred vision, constipation, and weight gain. These side effects are usually mild and temporary, but if they persist or become bothersome, it is important to inform your healthcare provider.
In some cases, Silenor may cause more serious side effects, such as an allergic reaction, hallucinations, irregular heartbeat, or difficulty urinating. If you experience any unusual or severe symptoms, it is important to seek immediate medical attention.
It is worth noting that Doxepin may interact with other medications, including certain antidepressants, antifungal drugs, and medications that affect the liver enzymes responsible for metabolizing drugs. Therefore, it is crucial to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements.
In conclusion, Doxepin is a medication used to treat insomnia. It is taken orally in tablet form, usually about 30 minutes before bedtime. It is important to follow the prescribed dosage and instructions provided by your healthcare provider. Maintaining a consistent sleep schedule and avoiding alcohol and other sedating substances can help maximize the effectiveness of Silenor. If you experience any concerning side effects or if your insomnia persists or worsens, it is important to consult with your healthcare provider for further guidance.
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