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Tiletamine is a dissociative anesthetic drug that is primarily used in veterinary medicine. It is often combined with the sedative zolazepam to form a medication known as Telazol. Telazol is commonly used for the induction and maintenance of anesthesia in animals, particularly in cats and other small animals
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Tiletamine belongs to the class of drugs known as NMDA receptor antagonists. It works by blocking the activity of N-methyl-D-aspartate (NMDA) receptors in the brain, which are involved in the transmission of pain signals and the regulation of consciousness. By inhibiting NMDA receptors, tiletamine produces a dissociative state, which is characterized by a profound anesthetic effect and a disconnection from the surrounding environment.
The combination of Telazol and zolazepam in Telazol produces a balanced anesthesia, with tiletamine providing the dissociative and anesthetic effects, while zolazepam acts as a sedative and muscle relaxant. This combination allows for smooth and reliable induction of anesthesia, as well as a quick and smooth recovery after the procedure.
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In veterinary medicine, Telazol is commonly used for various procedures, including surgical interventions, diagnostic procedures, and minor manipulations. It provides a fast onset of action and a relatively short duration of effect, which is advantageous in many veterinary settings.
The effects of tiletamine can vary depending on the species, dosage, and route of administration. In general, tiletamine induces a state of unconsciousness and analgesia, allowing for pain-free surgery or procedures. It also causes muscle relaxation, which is beneficial during surgical interventions.
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It is important to note that Telazol is primarily used in veterinary medicine and is not approved for human use. Its use in humans is limited to specialized situations, such as in certain research settings or for anesthetic purposes in exotic animals. As with any medication, tiletamine can have side effects. Common side effects observed in animals include respiratory depression, decreased heart rate, and decreased blood pressure. These effects are generally well-tolerated, but they can be more pronounced in animals with pre-existing respiratory or cardiovascular conditions.
In some cases, animals may exhibit excitement or disorientation during the recovery phase after the administration of Telazol. This is known as the “emergence reaction” and is more common in cats. It typically resolves on its own within a short period, but in some cases, additional medications may be used to manage this reaction.
Due to its potential for abuse and misuse, Telazol is classified as a controlled substance in many countries. It is regulated and restricted to veterinary use only. This classification helps prevent its unauthorized use and safeguard animal welfare.
It is important to note that the information provided here is a general overview and does not replace professional veterinary advice. The use of tiletamine and Telazol should always be performed under the guidance of a licensed veterinarian who can determine the appropriate dosage, administration route, and monitoring for the specific animal.
If you have any questions or concerns about tiletamine or its use in veterinary medicine, it is crucial to consult with a veterinarian. They can provide you with personalized information and guidance based on the specific needs of your pet or animal patient.
Please note that the information provided here is accurate as of my knowledge cutoff in September 2021. It is always recommended to consult the latest veterinary literature and guidelines for the most up-to-date information on tiletamine and its use in veterinary medicine.
Telazol is a nonnarcotic, nonbarbiturate, injectable anesthetic agent for dogs and cats. Chemically, TELAZOL is a combination of equal parts by weight of base of tiletamine hydrochloride (2-[ethylamino]-2-[2-thienyl]-cyclohexanone hydrochloride)
An arylaminocycloalkanone dissociative anesthetic, and zolazepam hydrochloride (4-[o-fluorophenyl]-6, 8-dihydro-1,3,8- trimethylpyrazolo [3, 4-e] [1,4] diazepin-7 [1H]-1- hydrochloride), a non-phenothiazine diazepinone having minor tranquilizing properties.
The product is supplied sterile in vials. The addition of 5 mL diluent produces a solution containing the equivalent of 50 mg tiletamine base, 50 mg zolazepam base and 57.7 mg mannitol per milliliter. This solution has a pH of 2 to 3.5 and is recommended for deep intramuscular injection. Buy Tiletamine Online, Dog anesthesia, Cat anesthesia.
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Telazol is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride. Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeallaryngeal reflexes and cataleptoid anesthesia.
The anesthetic state produced does not fit into the conventional classification of stages of anesthesia, but instead TELAZOL produces a state of unconsciousness which has been termed “dissociative’’ anesthesia in that it appears to selectively interrupt association pathways to the brain before producing somesthetic sensory blockade. Buy Tiletamine Online, Dog anesthesia, Cat anesthesia.
Cranial nerve and spinal reflexes remain active; however, these reflexes must not be confused with inadequate anesthesia. Analgesia results from apparent selective interruption of sensory inputs to the brain and usually persists after the anesthetic effect has subsided.
Protective reflexes, such as coughing and swallowing, are maintained under tiletamine anesthesia. Other reflexes, e.g., corneal, pedal, are maintained during tiletamine anesthesia, and should not be used as criteria for judging depth of anesthesia. The eyes normally remain open with the pupil dilated. It is suggested that a bland ophthalmic ointment be applied to the cornea if anesthesia is to be prolonged. Buy Tiletamine Online, D
Used alone, TELAZOL hydrochloride does not provide adequate muscle relaxation for abdominal surgical procedures. When combined with zolazepam hydrochloride, good muscle relaxation is generally attained during the phase of deep surgical anesthesia.
Following a single, deep intramuscular injection of TELAZOL in cats and dogs, onset of anesthetic effect usually occurs within 5 to 12 minutes. Muscle relaxation is optimum for approximately the first 20 to 25 minutes after TELAZOL is administered, and then diminishes. , TELAZOL Dog anesthesia, Cat anesthesia.
Recovery varies with the age and physical condition of the animal and the dose of TELAZOL administered, but usually requires several hours. Recovery is extended with multiple injections, particularly in cats. Quality TELAZOL for Sale Online, Dog and Cat anesthesia .
Repeated doses increase the duration of the effect of TELAZOL but may not further diminish muscle tone. The quality of anesthesia with repeated doses varies because the ratio of the two components within the animal’s body changes with each injection. This is due to the difference in the rates of metabolism and elimination of the two components.
The quality of anesthesia will be improved and more predictable if the entire dose is given as a single injection rather than in several doses. The best method of evaluating the depth of TELAZOL anesthesia is to monitor the patient for deliberate conscious response to nociceptive stimuli. Buy Tiletamine Online, Dog anesthesia, Cat anesthesia.
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